I started my Buserelin (Suprecur) injections on Thursday night last week after a bit of concern that I may not be able to. I ended up having to see my GP on Wednesday for a UTI that wouldn't go away and was put on Trimethoprim antibiotics. I spent all of Thursday desperately trying to get hold of someone at the clinic to make sure I could still start the injections and there wouldn't be any adverse drug reactions. Finally, one of the nurses got back to me and told me that it was absolutely fine as the drugs wouldn't react together and I didn't need to worry about it affecting the transfer because for the next 2 weeks they're only suppressing my ovaries and I have a good 4 weeks (minimum) until transfer.
The antibiotics themselves have been worse than any of the IVF meds I've had so far. I always get horrible nausea with antibiotics and this has been no exception. I've really been having to force myself to eat, but I've still managed to get to the gym and they've cleared up the UTI so I can't complain.
As I said above, the first injection was on Thursday night. We had some experience as this was the same medication we used for trigger so we knew what we were doing in terms of dosage etc. I've found that my stomach has bruised more with these injections - when I was doing the Gonal F and Cetrotide I only had one bruise the whole time, despite easy bruising being one of the problems I experience due to my EDS. They're quite uncomfortable as well and take a bit of force to go in. I can only put this down to the needle getting somewhat blunted pushing it through the rubber into the bottle to draw up the liquid. A lot of people have suggested switching needle but we don't have enough to use 2 a day. Either way it's really not that bad. It's more painful when the liquid is injected in (speed doesn't seem to make a difference here) but again it's more of an annoyance than anything and is over quickly.
After the injection I have had a localised reaction every time. It gets really red in a large patch around the injection site and itches like hell. Where I injected 2 days ago has randomly started itching and going red tonight which is odd so I'm avoiding that area.
All in all, they're more of a pain than the Gonal F or Cetrotide BUT still far from unbearable and only once a day.
Happy injecting!
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